pharmaceutical intermediates

Entrectinib

Identification
Name Entrectinib
Synonyms N-[5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methyl-1-piperazinyl)-2-[(tetrahydro-2H-pyran-4-yl)amino]benzamide; RXDX 101
copyRight
Molecular Structure CAS # 1108743-60-7, Entrectinib, N-[5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methyl-1-piperazinyl)-2-[(tetrahydro-2H-pyran-4-yl)amino]benzamide, RXDX 101
Molecular Formula C31H34F2N6O2
Molecular Weight 560.64
CAS Registry Number 1108743-60-7
INQUIRY

API 99% CAS 1108743-60-7 Entrectinib Powder
Product Description

Item Name: Entrectinib
CAS NO.: 1108743-60-7
Apparence:White Powder
Place of Origin: China (Mainland)
Assay:No less than 99%
Packaging Details:100g,1kg/bag, 25kg/drum API 99% CAS 1108743-60-7 Entrectinib Powder

Introduction of Entrectinib :

Entrectinib is an orally bioavailable inhibitor of the tyrosine kinases tropomyosin receptor kinases (Trk) A, B and C, C-ros oncogene 1 (ROS1) and anaplastic lymphoma kinase (ALK), with potential antineoplastic activity.

Function of Entrectinib :

Entrectinib is a tyrosine kinase inhibitor which acts on several receptors. It functions as an ATP competitor to inhibit tropomyosin receptor tyrosine kinases (TRK) TRKA, TRKB, TRKC, as well as proto-oncogene tyrosine-protein kinase ROS1 and anaplastic lymphoma kinase (ALK)

Packaging & Shipping.

API 99% CAS 1108743-60-7 Entrectinib Powder

By Express	By Air	By Sea
Suitable for under 1kg	Suitable for more than 1kg	Suitable for more than 10kg
Fast: 3-7 days	Fast: 5-9 days	Slow: 10-30 days
High cost	Medium cost	Low cost
Door to door service	Port to port service	Port to port service