Veterinary medicine Powder

Amprolium

Identification
Name Amprolium
Synonyms 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride
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Molecular Structure CAS # 121-25-5, Amprolium, 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride
Molecular Formula C14H19ClN4
Molecular Weight 278.78
CAS Registry Number 121-25-5
EINECS 204-458-4
INQUIRY

Introduction

Amprolium Hydrochloride(INN, trade names Amprovine, Amprolium, Amprol, Anticoccid) is a coccidiostat used in poultry.
Amprolium HCL is a thiamine analogue and blocks the thiamine transporter of Eimeria species. By blocking thiamine uptake it prevents carbohydrate synthesis.

Function

1. Amprolium hcl has a strong control effect on various coccidiosis.
2. Amprolium hcl is used to prevent and treat coccidiosis in poultry.
3. Amprolium hcl is mainly used to treat diarrhoeal coccidiosis, rectal bleeding, lack of energy, loss of appetite,dark feathers,paralysis and so on.

Application

Amprolium HCl /Amprolium Hydrochloride mainly used as veterinary drug to prevent and treat coccidiosis in poultry.
Amprolium HCl /Amprolium Hydrochloride mainly used to treat diarrhoeal coccidiosis, rectal bleeding, lack of energy, loss of appetite,dark feathers, paralysis and so on.

Animal Deworming Powder Amprolium Hydrochloride / Amprolium HCl

Items	Requirements	Results
Appearance:	White to Off-white powder	White to Off-white powder
Identification	A. IR B. HPLC	Conforms
Loss on drying	≤0.5%	0.1%
Identification A	IR spectrum corresponds to the reference chloramphenicol standard	Conforms
Melting Point	239-243°C	240°C
Related Substance	Individual impurity ≤1.0% Total impurity ≤2.0%	0.1% 0.7%
Heavy metal Pb : Cadmium(Cd) : As : Hg:	≤ 10ppm <1 ppm <0.5 ppm <10ppm < 1 ppm	<10ppm Conforms 0.3ppm Conforms Negative
Residue on ignition	≤0.2%	0.04%
Assay (HPLC)	98.0%~102.0%	99.3%
Conclusion:	The product conforms to BP.

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