cosmetic raw materials > Hair Growth >

minoxidil

Name Minoxidil
Synonyms 2,4-Diamino-6-piperidino-pyrimidine-3-oxide; 6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide; Loniten; Regain; Rogaine
copyRight
Molecular Structure CAS # 38304-91-5 (16317-69-4), Minoxidil, 2,4-Diamino-6-piperidino-pyrimidine-3-oxide, 6-(1-Piperidinyl)-2,4-pyrimidinediamine-3-oxide, Loniten, Regain, Rogaine
Molecular Formula C9H15N5O
Molecular Weight 209.25
CAS Registry Number 38304-91-5 (16317-69-4)
INQUIRY

Description

Product Name:	Minoxidil
Appearance:	White White to off white crystalline powder
CAS NO.:	38304-91-5
EINECS No:	253-874-2
Molecular Formula:	C9H15N5O
Assay:	98% min

Introduction:

Minoxidil is clinically used as a potassium channel opener, which can directly relax vascular smooth muscles and has a strong arterial expansion effect, which reduces peripheral resistance and blood pressure, but has no effect on volume vessels, so it can promote venous return. At the same time, due to the effect of reflex regulation and positive frequency, cardiac output and heart rate can be increased, but it does not cause orthostatic hypotension.

Function

1. Minoxidil is the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). It is used to treat high blood pressure including hair growth and male alopecia.
2. Minoxidil can be used for refractory hypertension and renal hypertension
3. Minoxidil is a vasodilator and antihypertensive drug, which opens the K + channel, so that the vascular smooth muscle does not cause orthostatic hypotension and has no long-term drug efficacy.

Application

1) Promote hair regrowth.
2) Slow or stop hair loss.
3) Treat high blood pressure.

Specifications:

TEST ITEMS	SPECIFICATION	RESULTS
Description	: White Crystalline Powder	White Powder
Identification	: Positive	Positive
Assay(by HPLC)	: 98.0~102.0%	99.34%
Absorbance(E1cm)	: 465~495	482.5
Melting Point	: 191~195°C	193.5~195.0°C
Loss On Drying	: 0.5%max	0.19%
Specific Rotation	: +288°~ +298°	+290.2°
Residue On Ignition	: 0.1%max	0.03%
Related Substances	: Total:1.5%max	<1.3%
	Single:0.5%max	<0.4%
Residue Solvents	: 0.2%max	0.10%
Heavy Metals	: 20PPm max	<10PPm
Conclusion	The specification conform with enterprise standard.