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  • Azithromycin


  • Identification
  • Name Azithromycin
  • Synonyms 9-Deoxo-9a-methyl-9a-aza-homoerythromycin A; (2R,3S,4R,5R,8R,10R,11R,13S,14R)-11-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
  • copyRight
  • Molecular Structure CAS # 83905-01-5, Azithromycin, 9-Deoxo-9a-methyl-9a-aza-homoerythromycin A, (2R,3S,4R,5R,8R,10R,11R,13S,14R)-11-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
  • Molecular Formula C38H72N2O12
  • Molecular Weight 748.99
  • CAS Registry Number 83905-01-5

product  Description:

Azithromycin is antibiotics.The antibacterial spectrum of this product is similar to erythromycin, with strong effect on haemophilus influenzae and gonococci, which is 4 times stronger than erythromycin.Twice as strong for legionella;For the vast majority of gram-negative bacteria, the effect on clostridium difficile is also stronger than erythromycin, in the application of staphylococcus aureus infection is also more effective than erythromycin.In addition, this product also has a good killing effect on toxoplasmosis, treponema pallidum.

Manufacturer Supply Azithromycin CAS83905-01-5 Azithromycin API



AppearanceWhite or almost white powderWhite powder
SolubilityPractically insoluble in water, freely soluble in anhydrous ethanol and in methylene chlorideConforms
Idetification1) IR: Conforms to the spectrum of Azithromycin RSConforms
2) HPLC: The retention time of azithromycin peak in the chromatogram of the assay preparation corresponds to that in the
chromatogram of the Standard preparation, as ovtained in the assay
Specific rotation-45°~ -49°-47°
CrystallinityMeets the requirementsConforms
pH9.0~11.0 (2mg/ml methanol-water(1:1))10.1
Residue on ignition≤0.3%0.01%
Heavy metals≤25ppm<25ppm
Impurity A ≤0.5%Not detected
Impurity B ≤1.0%0.40%
Impurity C ≤0.5%0.22%
Impurity J ≤0.3%0.11%
Impurity E ≤0.5%Not detected
Impurity F ≤0.5%<0.10%
Impurity G ≤0.5%Not detected
Related Substances(HPLC Test 2)Impurity I ≤0.7%Not detected
Impurity L≤0.5%Not detected
Impurity M≤0.5%Not detected
Impurity N ≤0.5%Not detected
Impurity O≤0.5%0.11%
Impurity P ≤0.2%<0.10%
Any other impuirty ≤0.2%<0.10%
Total impurities ≤3.0%0.84%
Residual SolventsMethylene Chlorde≤600ppmNot detected
Acetone ≤5000ppm330ppm
Assay945~1030μg/mg (Anhydrous substance )978μg/mg
ConclusionThe results can conforms with the USP37 standard.


1.Azithromycin is used to treat or prevent certain bacterial infections, most often those causing middle ear i nfections, strep throat, pneumonia, typhoid, and sinusitis;

2.It has been used primarily to prevent bacterial infections in infants and those with weaker immune system

3.It is also effective against certain sexually transmitted infections, such as non- gonococcal urethritis, chlamydia, and cervicitis;

4.Azithromycin is used for acute pharyngitis, acute tonsillitis caused by Streptococcus pyogenes;

5.Azithromycin is used for acute throat and tonsillitis which are caused by streptococcus pyogenes, otitis;

6.Azithromycin can treatment of media sinusitis acute bronchitis skin soft tissue infection which are caused by sensitive bacteria;

7.Azithromycin is also used for pneumonia urethritis cervicitis and so on.

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