Products Description
Product Name: | Paclitaxel |
Other Name | Taxol |
Source: | taxus |
Part of Used: | bark |
Test Method: | HPLC |
Specification: | 98% 99% |
CAS: | 33069-62-4 |
MF: | C47H51NO14 |
MW: | 853.91 |
EINECS | 608-826-9 |
Appearance: | Fine Powder |
Taste: | Characteristic |
Supplier Name: | ShaanXi Greenyo Biotech Co.,Ltd |
Shelf Life: | 2 years |
Package: | 1kg/foil bag(net weight 1kg, gross weight 1.2kg), 25kg/fiber drum(net weight 25kg, gross weight 28kg) |
Storage: | Stored in a cool and dry well closed container and in ventilated area, kept away from moisture and strong light or high temperature. |
Function
Paclitaxel is a monomer diterpene extracted from the bark of taxus, a natural plant. It is a complex secondary metabolite and the only known drug that can promote and stabilize the polymerized microtubules.Isotopic tracers indicate that paclitaxel binds only to the polymerized tubules and does not react with the unpolymerized tubuloprotein dimer.Cells exposed to paclitaxel accumulate a large number of microtubules, which interfere with the cell's various functions, especially by stopping cell division at the mitotic stage and preventing normal cell division.Through the II-III clinical research, paclitaxel is mainly suitable for ovarian cancer and breast cancer, to lung cancer, colorectal cancer, melanoma, head and neck cancer, lymphoma, brain tumors also has certain curative effect.
Application
It has a good effect on refractory ovarian cancer and breast cancer with drug resistance such as ovarian cancer and platinum, and a good prospect for the treatment of prostate cancer, head and neck cancer, esophageal cancer, germ cell tumor, endometrial cancer, lymphoma, bladder cancer, upper digestive tract cancer, small cell and non-small cell lung cancer.
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