pharmaceutical intermediates

Meropenem

Identification
Name Meropenem
Synonyms (4R,5S,6S)-3-[[(3S,5S)-5-Dimethylcarbamoylpyrrolidin-3-
copyRight
Molecular Structure CAS # 96036-03-2, Meropenem, (4R,5S,6S)-3-[[(3S,5S)-5-Dimethylcarbamoylpyrrolidin-3-
Molecular Formula C17H25N3O5S
Molecular Weight 383.46
CAS Registry Number 96036-03-2
INQUIRY

Product description

Item Name	Meropenem
CAS NO	96036-03-2
Appearance	White Powder
package	Aluminum Bag;Drums
Purity	99%
Storage	Store in a tightly closed container and cool dry place where the temperature stays below 20ºC

Function

Meropenem is bactericidal except against Listeria monocytogenes where it is bacteriostatic. It inhibits bacterial wall synthesis like other beta-lactam antibiotics. In contrast to other beta-lactams, it is highly resistant to degradation by beta-lactamases or cephalosporinases. Resistance generally arises due to mutations in penicillin binding proteins, production of metallo-beta-lactamases, or resistance to diffusion across the bacterial outer membrane. Unlike imipenem, it is stable to dehydropeptidase-1 and can therefore be given without cilastatin.